Holding Hands: Using Peptide-Drug Conjugates (PDCs) for the Precise Treatment of Pulmonary Fibrosis on October 27, 2024 in New Jersey, United States
- Event Type: Seminar
- Presentation: Digital
- Website URL: https://www.bocsci.com/holding-hands-using-peptide-drug-conjugates-pdcs-for-the-precise-treatment-of-pulmonary-fibrosis.html
- Contact E-mail: [email protected]
- Location: New Jersey, United States
- Date: October 27, 2024
- Final Submission: November 27, 2024
- Organization: BOC Sciences
- Seminar Tags: biochemistry biochemical pharmacology bioanalytical chemistry agrochemicals agricultural chemistry
Targeted therapy is a new paradigm in biomedical research that improves therapeutic efficacy, overcomes drug resistance, reduces off-target effects, and enables early disease detection by precisely delivering drugs to diseased tissue. Peptide drug conjugates (PDCs), a new tool for targeted therapy, consist of a targeting peptide, a linker, and an active drug. Dr Kelly's team synthesized a PDC series of PDCs designed to treat pulmonary fibrosis precisely, combining the kinase inhibitor nintedanib with a mimetic peptide chain targeting the αVβ6 integrin. Their antifibrotic activity is currently being evaluated in a mouse model of pulmonary fibrosis.
Name: BOC Sciences
Website: https://www.bocsci.com
Address: New York City, USA
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